Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Assay Kits  >  MMP Assay Kits  >>  SensoLyte® Generic MMP Assay Kit “Colorimetric”

Product Name SensoLyte® Generic MMP Assay Kit “Colorimetric”
Size 1 kit
Catalog # AS-72095
US$ $298
Description

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. The SensoLyte® Generic MMP Assay Kit can be used to detect the activity of a variety of MMPs, including MMP-1, 2, 3, 7, 8, 9, 12, 13, and 14 or for high throughput screening of MMPs’ inducers and inhibitors. The substrate is a thiopeptolide that is cleaved by the MMPs, releasing a sulfhydryl group, which can be detected with a color-developing thiol-reactive agent, 4,4’-dithiodipyridine or Ellman’s Reagent at 412 nm using a microplate reader. The assays are performed in a convenient 96-well microplate format.

Kit size: 100 assays

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Brochure
Storage -20°C
Product Citations Spolidoro, M. et al. (2013). Inhibition of matrix metalloproteinases prevents the potentiation of nondeprived-eye responses after monocular deprivation in juvenile rats. Cereb Cortex 22, 725. doi: 10.1093/cercor/bhr158.
Li, R. et al. (2012). A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases. Am J Physiol Cell Physiol 302, C658-C665.
Tezvergil-Mutluay, A. et al. (2012). Carbodiimide cross-linking inactivates soluble and matrix-bound MMPs, in vitro JDR 91, 192-196.
Thompson, J. et al. (2012). Inhibition of endogenous dentin matrix metalloproteinases by ethylenediaminetetraacetic acid. JOE,38, 62.
Tezvergil-Mutluay, A. et al. (2011). The Inhibitory Effects of Quaternary Ammonium Methacrylates on Soluble and Matrix-bound MMPs. JDR doi: 10.1177/0022034510389472.
Tezvergil, A. et al. (2010). The inhibitory effect of polyvinylphosphonic acid on functional MMP activities in human demineralized dentin. Acta Biomaterialia doi:10.1016/j.actbio.2010.05.017.
     
  < Back