This amino acids 52 to 71 fragment of the BH3 domain of Bim reportedly functions as direct 'death agonist' of Bax. Bim belongs to a distinct subgroup of proapoptotic proteins that resemble other Bcl-2 family members within the BH3 domain.
Storage
-20°C
References
O’Reilly, L. et al. Am. J. Pathol. 157, 449 (2000), Letai A, et al. Canc. Cell 2, 183 (2002), Cartron, P. et al. Mol. Cell 16, 807 (2004), Manero, F. et al. Canc. Res. 66, 2757 (2006).
Molecular Weight
2485.9
Sequence (One-Letter Code)
Ac-MRPEIWIAQELRRIGDEFNA
Sequence (Three-Letter Code)
Ac - Met - Arg - Pro - Glu - Ile - Trp - Ile - Ala - Gln - Glu - Leu - Arg - Arg - Ile - Gly - Asp - Glu - Phe - Asn - Ala - NH2
