This Bax H2-H3 peptide is amino acids 53 to 86 fragment of Bax which contains the BH3 helix plus residues in the downstream helix 3 (amino acids 74–81). Cultured cells injected with the H2-H3 peptide result in morphological changes consistent with apoptosis, including plasma membrane blebbing. H2-H3 peptide mimics Bax auto-activation.
Storage
-20°C
References
Tan, C. et al. J. Biol. Chem 281, 14764 (2006).
Molecular Weight
3797.3
Sequence (One-Letter Code)
DASTKKLSECLKRIGDELDSNMELQRMIAAVDTD
Sequence (Three-Letter Code)
H - Asp - Ala - Ser - Thr - Lys - Lys - Leu - Ser - Glu - Cys - Leu - Lys - Arg - Ile - Gly - Asp - Glu - Leu - Asp - Ser - Asn - Met - Glu - Leu - Gln - Arg - Met - Ile - Ala - Ala - Val - Asp - Thr - Asp - OH
