| Product Name |
Bak BH3 (73 - 87) |
| Size |
1 mg |
| Catalog # |
62480 |
| US$ |
$95 |
| Molecular Weight |
1667.9 |
Sequence
(One-Letter Code) |
QVGRQLAIIGDDINR |
Sequence
(Three-Letter Code) |
H - Gln - Val - Gly - Arg - Gln - Leu - Ala - Ile - Ile - Gly - Asp - Asp - Ile - Asn - Arg - OH |
| Description |
This is amino acids 73 to 87 fragment of Bak BH3 protein. Synthetic BH3 peptides can bind to Bcl-2-like death suppressors and block heterodimerization with pro-apoptotic Bcl-2 homologs in vitro. Bak BH3 peptides bind to Bcl-XL and interfere with its anti-apoptotic function. This 15-amino acid Bak BH3 peptide greatly attenuates the protective effect of Bcl-XL. |
| References |
Holinger, E. et al. J. Biol. Chem. 274, 13298 (1999). |
| Storage |
-20°C |
| Detailed Information |
 Material Safety Data Sheets (MSDS)
|
