H - Ala - Phe - Leu - Ser - Val - Lys - Lys - Gln - Phe - OH
Description
This is amino acids 85 to 93 fragment of survivin derived from the exon 3-encoded region. Survivin has a capability to inhibit caspase-3, -7, and -9 in the cells receiving apoptotic stimulus.
References
Hirohashi, Y. et al. Clin. Canc. Res. 8, 1731 (2002).