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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  TAT-NSF700 Fusion Peptide

Product Name TAT - NSF700 Fusion Peptide
YGRKKRRQRRR - GGG - LLDYVPIGPRFSNLVLQALLVL
Size 1 mg
Catalog # AS-62238
US$ $325
Description

This peptide is the N-Ethyl-maleimide-sensitive factor (NSF) inhibitor fusion polypeptide composed of 11-amino acid cell permeable HIV transactivating regulatory protein (TAT) domain fused to a 22 amino acid NSF domain. TAT-NSF700 inhibits thrombin-induced exocytosis of endothelial cells in a dose-responsive manner.

Detailed Information Datasheet
Storage -20C
References Matsushita, K. et al. Mol. Pharmacol. 67,1137 (2005).
Molecular Weight 4167
Sequence
(One-Letter Code)
YGRKKRRQRRR-GGG-LLDYVPIGPRFSNLVLQALLVL
Sequence
(Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Gly - Gly - Gly - Leu - Leu - Asp - Tyr - Val - Pro - Ile - Gly - Pro - Arg - Phe - Ser - Asn - Leu - Val - Leu - Gln - Ala - Leu - Leu - Val - Leu - OH
Product Citations Trang, T. et al. (2009). P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation. J Neurosci 29, 3518.
Matsushita, K. et al. (2005). A Novel Class of Fusion Polypeptides Inhibits Exocytosis. Mol Pharmacol 67, 1137.
     
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