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Peptides  >  MHC related   >>  Adeno-Associated Virus Epitope 2 (AAV2)

Product Name Adeno - Associated Virus Epitope 2 (AAV2)
VPQYGYLTL
Size 1 mg
Catalog # AS-62522
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is the capsid derived immunodominant adeno-associated virus 2 (AAV2), CD8 T cell epitope. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.

Storage -20C
References Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006), Mingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007), Wang, L. et al. Therapy. 18, 185 (2007).
Molecular Weight 1053.2
Sequence
(One-Letter Code)
VPQYGYLTL
Sequence
(Three-Letter Code)
H - Val - Pro - Gln - Tyr - Gly - Tyr - Leu - Thr - Leu - OH
     
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