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Peptides  >  Neuropeptides  >>  Glutamate Receptor Endocytosis Inhibitor, GluR23Y

Product Name Glutamate Receptor Endocytosis Inhibitor, GluR23Y
YKEGYNVYG
Size 1 mg
Catalog # AS-62547
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.

Storage -20C
References Ahmadian, G. et al. EMBO J. 23, 1040 (2004), Wang, D. et al. J. Biol. Chem. 279, 41267 (2004).
Molecular Weight 1092.2
Sequence
(One-Letter Code)
YKEGYNVYG
Sequence
(Three-Letter Code)
H - Tyr - Lys - Glu - Gly - Tyr - Asn - Val - Tyr - Gly - OH
     
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