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Peptides  >  Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)  >>  MOG (101-120), human, mouse

Product Name MOG (101 - 120), human, mouse
RDHSYQEEAAMELKVEDPFY
Size 1 mg
Catalog # AS-62370
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This is amino acids 101 to 120 fragment of myelin oligodendrocyte glycoprotein (MOG), one of the major MOG B-cell epitopes in transgenic mice. MOG is a potential target antigen of the central nervous system known to induce autoreactive T cell response and demyelinating anti-MOG antibodies in multiple sclerosis (MS) patients. Studies demonstrated that a quantitatively minor myelin protein, MOG, is also strongly encephalogenic in mice, rats, marmosets, and rhesus monkeys, which is highly relevant to MS.

Storage -20C
References Khare, M. et al. Int. Immunol. 15, 535 (2003).
Molecular Weight 2457.7
Sequence
(One-Letter Code)
RDHSYQEEAAMELKVEDPFY
Sequence
(Three-Letter Code)
H - Arg - Asp - His - Ser - Tyr - Gln - Glu - Glu - Ala - Ala - Met - Glu - Leu - Lys - Val - Glu - Asp - Pro - Phe - Tyr - OH
     
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