This is amino acids 101 to 120 fragment of myelin oligodendrocyte glycoprotein (MOG), one of the major MOG B-cell epitopes in transgenic mice. MOG is a potential target antigen of the central nervous system known to induce autoreactive T cell response and demyelinating anti-MOG antibodies in multiple sclerosis (MS) patients. Studies demonstrated that a quantitatively minor myelin protein, MOG, is also strongly encephalogenic in mice, rats, marmosets, and rhesus monkeys, which is highly relevant to MS.
Storage
-20°C
References
Khare, M. et al. Int. Immunol. 15, 535 (2003).
Molecular Weight
2457.7
Sequence (One-Letter Code)
RDHSYQEEAAMELKVEDPFY
Sequence (Three-Letter Code)
H - Arg - Asp - His - Ser - Tyr - Gln - Glu - Glu - Ala - Ala - Met - Glu - Leu - Lys - Val - Glu - Asp - Pro - Phe - Tyr - OH
