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Peptides  >  Histones  >  Histone H4 Peptides  >>  Histone H4 (1-7), N-Terminal

Product Name Histone H4 (1 - 7), N - Terminal
SGRGKGG
Size 1 mg
Catalog # 62754
US$ $66
Purity % Peak Area By HPLC ≥ 95%
Description

This is amino acids 1 to 7 fragment of the histone H3. Alterations in chromatin structure, such as nucleosome sliding, removal of nucleosomes, and disruption of DNA–histone or histone–histone contacts through post-translational modification of the histones, have been linked to transcriptional regulation, DNA damage repair, and replication, among other cellular processes. Modification of histones occurs primarily in the N-terminal residues or tail region. These modifications include phosphorylation, ubiquitinylation, methylation, sumolyation, and acetylation. Lys5 may serve as the acetylation site for this peptide.

Storage -20°C
References Berndsen, C. et al. Biochem. 46, 2091 (2007).
Molecular Weight 617.7
Sequence
(One-Letter Code)
SGRGKGG
Sequence
(Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - OH
     
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