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Peptides  >  Histones  >  Histone H4 Peptides  >>  Histone H4 (1-21), p300/CBP Substrate

Product Name Histone H4 (1 - 21), p300/CBP Substrate
SGRGKGGKGLGKGGAKRHRKV
Size 1 mg
Catalog # 62499
US$ $176
Purity % Peak Area By HPLC ≥ 95%
Description

This sequence is amino acids 1 to 21 fragment of the histone 4. Histone acetyltransferase (HAT) p300/CBP catalyses the acetylation of this N-terminal tail of free histone H4 at Lys5, 8, 12, 16. Lys8 is thought to be the preferred acetylation site in H4. Determinants of interaction of p300 with histone 4 appear to be fully present on H4-21, the N-terminal region of the protein.

Detailed Information Datasheet
Storage -20C
References Sun, Y. et al. Mol. Cell. Biol. Oct 2007, 10.1128/MCB.01382-07.
Molecular Weight 2091.5
Sequence
(One-Letter Code)
SGRGKGGKGLGKGGAKRHRKV
Sequence
(Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - OH
     
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