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Peptides  >  Amyloid Peptides  >  Beta-Amyloid Peptide Fragments  >>  Beta-Amyloid (11-25), Human

Product Name Beta - Amyloid (11 - 25), Human
EVHHQKLVFFAEDVG
Size 1 mg
Catalog # 62884
US$ $93
Purity % Peak Area By HPLC ≥ 95%
Description

This amino acids 11 to 22 fragment of b-amyloid is capable of forming well-organized amyloid fibrils in vitro, similar to the pathogenic ones found in amyloidosis. Analysis of the structural properties of one monomer of b-amyloid (11-22) as well as of the aggregation mechanisms for four chains of b-amyloid (11-22) showed that the system assembles rapidly into a random globular state that evolves into three- and four-stranded antiparallel beta-sheets. The aggregation process is considerably accelerated by the presence of preformed dimers.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Boucher, G. et al. Proteins 65, 877 (2006); Tjernberg, L. et al. J. Biol. Chem. 274, 12619 (1999).
Molecular Weight 1755.0
Sequence
(One-Letter Code)
EVHHQKLVFFAEDVG
Sequence
(Three-Letter Code)
H - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - OH
     
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