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Peptides  >  Protein Phosphorylation Related Peptides  >>  S3 Fragment, ADF/cofilin

Product Name S3 Fragment, ADF/cofilin
MASGVMVSDDVVKVFN
Size 1 mg
Catalog # AS-62637
US$ $99
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.

Storage -20C
References Wen, Z. et al. J. Cell Biol. 178, 107 (2007).
Molecular Weight 1698.0
Sequence
(One-Letter Code)
MASGVMVSDDVVKVFN
Sequence
(Three-Letter Code)
H - Met - Ala - Ser - Gly - Val - Met - Val - Ser - Asp - Asp - Val - Val - Lys - Val - Phe - Asn - OH
     
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