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Peptides  >  Amyloid Peptides  >  Amyloid Toxicity Inhibitor Peptides  >>  Amyloid Toxicity Inhibitor Peptide 11

Product Name Amyloid Toxicity Inhibitor Peptide 11
RGTFEGKF - NH2
Size 1 mg
Catalog # 62834
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

Amyloid toxicity inhibitor peptide 11 is composed of hydrophilic and hydrophobic amino acids. The positively charged unprotected N-terminus allows it to interact with negatively charged C-terminus of b-amyloid 1 to 40. It was shown that this peptide is effective in blocking fibrillization of transmembrane peptide derived from glycophorin A containing a GxMxG motif. Glycophorin sequence can form fibrils with a cross b-structure as in b-amyloid. This peptide inhibits fibrillization by binding to the surface of the beta sheet.

Storage -20C
References Sato, T. et al. Biochem. 45, 5509 (2006).
Molecular Weight 940.1
Sequence
(One-Letter Code)
RGTFEGKF-NH2
Sequence
(Three-Letter Code)
H - Arg - Gly - Thr - Phe - Glu - Gly - Lys - Phe - NH2
     
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