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Peptides  >  Histones  >  Histone H3 Peptides  >>  Histone H3 (1-20), N-Terminal

Product Name Histone H3 (1 - 20), N - Terminal
ARTKQTARKSTGGKAPRKQL
Size 1 mg
Catalog # AS-62753
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This is amino acids 1 to 20 fragment of the histone H3. Comparison the acetylation efficiency of different substrates showed that this peptide corresponding to the N-terminal of H3 histone has nearly identical acetylation efficiency as the H4 peptides. Acetylation of histones is generally associated with active transcription, constitutes a post-translational mark recognized by specific chromatin factors, and has been shown in vitro to prevent salt-induced folding of nucleosome arrays. Multisubunit histone acetyltransferase (HAT) complexes recognize and perform efficient acetylation on nucleosome substrates.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Berndsen, C. et al. Biochem. 46, 2091 (2007).
Molecular Weight 2183.6
Sequence
(One-Letter Code)
ARTKQTARKSTGGKAPRKQL
Sequence
(Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - OH
     
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