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Peptides  >  Protein Phosphorylation Related Peptides  >>  [pS345]-Chk1

Product Name [pS345] - Chk1
QGISF - pS - QPTC
Size 1 mg
Catalog # 62819
US$ $176
Purity % Peak Area By HPLC ≥ 95%
Description

This is amino acids 340 to 349 fragment of Chk-1 protein, phosphorylated at Ser345. Chk1, an evolutionarily conserved protein kinase, has been implicated in cell cycle checkpoint control in lower eukaryotes in response to DNA damage and replicative stress. CHK1 deficiency results in a severe proliferation defect and death in embryonic stem cells, and peri-implantation embryonic lethality in mice.

Storage -20C
References Liu, Q. et al. Genes Dev. 14, 1448 (2000).
Molecular Weight 1147.2
Sequence
(One-Letter Code)
QGISF-pS-QPTC
Sequence
(Three-Letter Code)
H - Gln - Gly - Ile - Ser - Phe - pSer - Gln - Pro - Thr - Cys - OH
     
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