Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Cancer Research Peptides  >>  WP9QY, TNF-alpha Antagonist

Product Name WP9QY, TNF - alpha Antagonist
YCWSQYLCY (Disulfide bridge: 2 - 8)
Size 1 mg
Catalog # AS-62621
US$ $132
Purity % Peak Area By HPLC ≥ 95%
Description

This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.

Storage -20C
References Saito, H. et al. Arthritis Rheum. 56, 1164 (2007).
Molecular Weight 1226.4
Sequence
(One-Letter Code)
YCWSQYLCY (Disulfide bridge: 2-8)
Sequence
(Three-Letter Code)
H - Tyr - Cys - Trp - Ser - Gln - Tyr - Leu - Cys - Tyr - OH (Disulfide bridge: 2 - 8)
     
  < Back