WE-14 is a neuropeptide derived from the posttranslational processing of chromogranin A (CgA). While CgA is expressed in a preponderance of neuroendocrine cells, WE-14 is generated in a distinct subpopulation of CgA-immunopositive cells, most notably in the adrenal, pituitary, and parathyroid glands.
Curry, W. et al. Ann. N. Y. Acad. Sci.971, 311 (2002); Fälth, M. et al. Mol. Cell. Proteom.5, 998 (2006).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Trp - Ser - Arg - Met - Asp - Gln - Leu - Ala - Lys - Glu - Leu - Thr - Ala - Glu - OH