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Peptides  >  Protein Phosphorylation Related Peptides  >>  ε-V1-2, ε-PKC Inhibitor

Product Name ε - V1 - 2, ε - PKC Inhibitor
Size 1 mg
Catalog # 62186
US$ $71
Purity % Peak Area By HPLC ≥ 95%

This peptide is derived from residues 14-21 of protein kinase C C2 (εPKC C2). This peptide specifically inhibits εPKC by disrupting PKC binding to its receptor, RACK2. εPKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Lamy, C. et al. Tetrahedron Lett 46, 6177 (2007). Brandman, R. et al. J. Biol. Chem. 282, 4113 (2007).
Molecular Weight 844
(One-Letter Code)
(Three-Letter Code)
H - Glu - Ala - Val - Ser - Leu - Lys - Pro - Thr - OH
Product Citations Khoury, NE. et al. (2014). Interleukin-1β reduces L-type Ca2+ current through Protein Kinase Cε activation in mouse heart. J Biol Chem 289, 21896. doi: 10.1074/jbc.M114.549642.
Roh, D. et al. (2010). Sigma-1 receptor-induced increase in murine spinal NR1 phosphorylation is mediated by the PKCα and var epsilon, but not the PKCζ, isoforms. Neurosci Lett 477, 95.
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