This peptide is amino acids 8 to 21 fragment of the myelin oligodendrocyte glycoprotein (MOG). It induces relapsing experimental autoimmune encephalomyelitis (EAE) in mice associated with broadening of the autoimmune repertoire. Subtle changes in MOG (8-21) dramatically influences disease susceptibility and T-cell responses in vitro.
Storage
-20°C
References
Heijmans, N. et al. J. Neuroimmunol. 167, 23 (2005), Smith, P. et al. J. Neuroimmunol. 164, 76 (2005).
Molecular Weight
1486.7
Sequence (One-Letter Code)
PGYPIRALVGDEAE
Sequence (Three-Letter Code)
H - Pro - Gly - Tyr - Pro - Ile - Arg - Ala - Leu - Val - Gly - Asp - Glu - Ala - Glu - OH
