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Peptides  >  Apoptosis Peptides  >>  PR39, Anti-Apoptotic Factor

Product Name PR39, Anti - Apoptotic Factor
RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Size 0.5 mg
Catalog # AS-63688-05
US$ $264
Purity % Peak Area By HPLC ≥ 95%
Description

Isolated originally from pig intestine, this proline and arginine rich 39 amino acid peptide is also found in neutrophil azurophilic granules and macrophages. This peptide plays a role in cell motility and metastatic potential in wound repair; binds to NADPH oxidase complex protein p47phox7 and a signaling adaptor protein p130Cas. And recently, PR39 is found to inhibit hypoxia-induced apoptosis and decrease caspase-3 activity in endothelial cells.

Storage -20C
References Wu, J. et al. Circulation 109, 1660 (2004).
Molecular Weight 4720.7
Sequence
(One-Letter Code)
RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Sequence
(Three-Letter Code)
H - Arg - Arg - Arg - Pro - Arg - Pro - Pro - Tyr - Leu - Pro - Arg - Pro - Arg - Pro - Pro - Pro - Phe - Phe - Pro - Pro - Arg - Leu - Pro - Pro - Arg - Ile - Pro - Pro - Gly - Phe - Pro - Pro - Arg - Phe - Pro - Pro - Arg - Phe - Pro - OH
     
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