This is amino acids 1 to 20 fragment of the myelin basic protein, MBP. MBP induces immune reactivity in multiple sclerosis (MS). MS is a chronic inflammatory demyelinating disease of the CNS. This sequence contains at least three T-cell immunodominant epitopes: MBP (1-9), MBP (9-20), and MBP (5-20).
Storage
-20°C
References
Bischof, F. et al. J. Immunol.173, 600 (2004); Fairchild, P. et al. Intl. Immun.8, 1035 (1996).
Molecular Weight
2226.5
Sequence (One-Letter Code)
ASQKRPSQRSKYLATASTMD
Sequence (Three-Letter Code)
H - Ala - Ser - Gln - Lys - Arg - Pro - Ser - Gln - Arg - Ser - Lys - Tyr - Leu - Ala - Thr - Ala - Ser - Thr - Met - Asp - OH