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Peptides  >  Cancer Research Peptides  >>  TRP-2 (180-188)

Product Name TRP - 2 (180 - 188)
SVYDFFVWL
Size 1 mg
Catalog # AS-61058
US$ $93
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 180-188. TRP2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class I molecules. Immunization with TRP2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity.

Storage -20C
References Park, J. et al. The EMBO J. 18, 3024 (1999); Bichsel, S. et al. J. Biol. Chem. 279, 35228 (2004)
Molecular Weight 1175.4
Sequence
(One-Letter Code)
SVYDFFVWL
Sequence
(Three-Letter Code)
H - Ser - Val - Tyr - Asp - Phe - Phe - Val - Trp - Leu - OH
     
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