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Peptides  >  Exendins  >>  [Des-His1, Glu8]-Exendin-4

Product Name [Des - His1, Glu8] - Exendin - 4
GEGTPTSELSKQMEEEAVRLPIEWLKNGGPSSGAPPPS - NH2
Size 1 mg
Catalog # AS-63900
US$ $303
Purity % Peak Area By HPLC ≥ 95%
Description

This is Exendin-4 in which the first amino acid (His) has been removed and Asp9 has been replaced with Glu9. Intracerebroventricular (ICV) administration of this peptide, [des-His1,Glu8]-Exendin-4, a GLP-1 antagonist, impairs glucose tolerance in mice.

Storage -20C
References Sandoval, DA. et al. Diabetes 7, 1824 (2008); Williams, DL. et al. Endocrin. 10, 1045 (2008).
Molecular Weight 3963.4
Sequence
(One-Letter Code)
GEGTPTSELSKQMEEEAVRLPIEWLKNGGPSSGAPPPS-NH2
Sequence
(Three-Letter Code)
H - Gly - Glu - Gly - Thr - Pro - Thr - Ser - Glu - Leu - Ser - Lys - Gln - Met - Glu - Glu - Glu - Ala - Val - Arg - Leu - Pro - Ile - Glu - Trp - Leu - Lys - Asn - Gly - Gly - Pro - Ser - Ser - Gly - Ala - Pro - Pro - Pro - Ser - NH2
     
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