Soymetide-4 (MITL) is a bioactive peptide, the minimal sequence required for phagocytosis stimulation. Soymetide is isolated from trypsin digests of soy protein. Met at N terminus of the soymetide is essential for the activity. Soymetide-4 promotes tumor necrosis factor A production at a higher level than soymetide-13 following oral administration in mice.
Maruyama, N. et al. Biochim. Biophys. Acta 1648, 99 (2003); Tsuruki, T. et al. Pepides 26, 707 (2005); Takahiro, T. et al. FEBS Lett. 540, 2436 (2003).