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Peptides  >  Pancreatic Polypeptides  >>  BDC2.5 Mimotope

Product Name BDC2.5 Mimotope
RTRPLWVRME
Size 1 mg
Catalog # 63774
US$ $77
Purity % Peak Area By HPLC ≥ 95%
Description

The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet β cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells.

Storage -20C
References Hu, C. et al. J. Clin. Invest. 117, 3857 (2007); Martin-Orozco, N. et al. J. Immunol. 171, 6954 (2003).
Molecular Weight 1343.6
Sequence
(One-Letter Code)
RTRPLWVRME
Sequence
(Three-Letter Code)
H - Arg - Thr - Arg - Pro - Leu - Trp - Val - Arg - Met - Glu - OH
     
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