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Peptides  >  Amyloid Peptides  >  Beta-Amyloid Peptide Fragments  >>  Beta-Amyloid (11-17), Human

Product Name Beta - Amyloid (11 - 17), Human
EVHHQKL
Size 1 mg
Catalog # AS-63819
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This is a short fragment of the b-Amyloid peptide containing Histidine 13 and 14. Alzheimer’s beta amyloid peptides form A? ion channels in lipid bilayers. It is postulated that ion channel activity of A? is related to cytotoxic activity of A?. Small peptides that contain the amino acid sequence of the predicted mouth region of the A? channel pore can inhibit A? ion channel activity. And, Histidines 13 and 14 have been shown to be essential for the peptide to inhibit Alzheimer’s disease A? ion channel and cytotoxicity.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C
References Arispe, N. J. Membrane Biol. 197, 33 (2004); Diaz, J.C. et al. Biol. Res. 39, 447 (2006)
Molecular Weight 890.0
Sequence
(One-Letter Code)
EVHHQKL
Sequence
(Three-Letter Code)
H - Glu - Val - His - His - Gln - Lys - Leu - OH
     
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