This peptide is amino acid residue 149 to 157 of chemerin, a natural ligand of ChemR23, a G protein-coupled receptor expressed in immature dendritic cells and macrophages. This peptide retains most of the activities of the full size protein including ligand binding to chemerin receptor.
Wittamer, V. et al. J. Biol. Chem. 279, 9956 (2004)
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Tyr - Phe - Pro - Gly - Gln - Phe - Ala - Phe - Ser - OH