Genetic transformation in Streptococcus pneumoniae, Streptococcus mitis and Streptococcus oralis is regulated by secreted peptide pheromones named the competence-stimulating peptide (CSP). Different strains and species of these bacteria produce CSP with different primary sequence. They are termed pheromones CSP-1 (EMRLSKFFRDFILQRKK), CSP-2 (EMRISRIILDFLFLRKK), CSP-153 (DKRLPYFFKHLFSNRTK), CSP-612 (ESRLSRLLRDFIFQIKQ), CSP-676 (ERRIPDVIRSLLFQKRK), and CSP-12261 (EIRQTHNIFFNFFKRR).
Storage
-20°C
References
Francis, K. et al. Infection Immunity 69, 3350 (2001); Johnsborg, O. et al. Mol. Microbio. 69, 245 (2008).
Molecular Weight
2178.7
Sequence (One-Letter Code)
EMRISRIILDFLFLRKK
Sequence (Three-Letter Code)
H - Glu - Met - Arg - Ile - Ser - Arg - Ile - Ile - Leu - Asp - Phe - Leu - Phe - Leu - Arg - Lys - Lys - OH