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Peptides  >  Antimicrobial and Related Peptides  >>  CSP-2, Competence-Stimulating Peptide-2

Product Name CSP - 2, Competence - Stimulating Peptide - 2
Size 1 mg
Catalog # 63877
US$ $105
Purity % Peak Area By HPLC ≥ 95%
Description

Genetic transformation in Streptococcus pneumoniae, Streptococcus mitis and Streptococcus oralis is regulated by secreted peptide pheromones named the competence-stimulating peptide (CSP). Different strains and species of these bacteria produce CSP with different primary sequence. They are termed pheromones CSP-1 (EMRLSKFFRDFILQRKK), CSP-2 (EMRISRIILDFLFLRKK), CSP-153 (DKRLPYFFKHLFSNRTK), CSP-612 (ESRLSRLLRDFIFQIKQ), CSP-676 (ERRIPDVIRSLLFQKRK), and CSP-12261 (EIRQTHNIFFNFFKRR).

Storage -20°C
References Francis, K. et al. Infection Immunity 69, 3350 (2001); Johnsborg, O. et al. Mol. Microbio. 69, 245 (2008).
Molecular Weight 2178.7
Sequence
(One-Letter Code)
EMRISRIILDFLFLRKK
Sequence
(Three-Letter Code)
H - Glu - Met - Arg - Ile - Ser - Arg - Ile - Ile - Leu - Asp - Phe - Leu - Phe - Leu - Arg - Lys - Lys - OH
Product Citations Coleman, J. et al. (2011). Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair bias. J Infect Dis doi: 10.1093/infdis/jir010.
     
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