Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  HIV Related Peptides  >>  HIV Substrate, HiLyte™ Fluor 488

Product Name HIV Substrate, HiLyte™ Fluor 488
QXL® 520 - GABA - SQNYPIVQ - K(HiLyte™ Fluor 488) - NH2
Size 0.1 mg
Catalog # AS-60635
US$ $115
Purity % Peak Area By HPLC ≥ 95%
Description

Ths is a HiLyte Fluor labeled HIV protease substrate I, GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS. The peptide sequence is derived from the native p17/p24 cleavage site on HIV precursor polyprotein Prgag for HIV-1 protease. Cleavage of HIV precursor polyproteins is essential for the maturation of the infectious virus and hence the protease has become a major target for developing anti-AIDS drugs. The peptide substrate is widely used for the continuous assay for HIV protease activity. The QXL/488 pair offers better sensitivity in detection at a higher wavelength with less background interference. (Excitation/Emission = 490 nm/520 nm).

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C
References 1, Seelmeier S, et al. Proc. Natl. Acad. Sci. USA 85, 6612 (1988).
2, Schneider J, and Kent SBH. Cell 54, 363 (1988).
3, Gehringer H et al. J. Virol. Methods 109, 143 (2003).
Molecular Weight 2008.1
Sequence
(One-Letter Code)
QXL® 520-GABA-SQNYPIVQ-K(HiLyte™ Fluor 488)-NH2
Sequence
(Three-Letter Code)
QXL® 520 - GABA - Ser - Gln - Asn - Tyr - Pro - Ile - Val - Gln - Lys(Hilyte™ Fluor 488) - NH2
     
  < Back