This NYAD-2 peptide is NYAD-1 labeled with FITC (Ex/Em=493/517 nm). NYAD-1 is a cell-penetrating alpha-helical peptide used as a potential HIV-1 inhibitor. The hydrocarbon-stapled structure enhances alpha helicity.
FITC-(beta-A)-ITFXDLLXYYGP-NH2 (with special cyclization to get double bond, X= (S)-alpha-(2’-pentenyl)alanine)
Sequence (Three-Letter Code)
FITC - (beta - Ala) - Ile - Thr - Phe - X - Asp - Leu - Leu - X - Tyr - Tyr - Gly - Pro - NH2 (with special cyclization to get double bond, X= (S) - alpha - (2’ - pentenyl)alanine)