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Peptides  >  Amyloid Peptides  >  Beta-Amyloid (1-28) and Related Peptides  >>  [Ala16,17,20]-β-Amyloid (1-28), Human

Product Name [Ala16,17,20] - β - Amyloid (1 - 28), Human
DAEFRHDSGYEVHHQAAVFAAEDVGSNK
Size 1 mg
Catalog # 62890
US$ $225
Purity % Peak Area By HPLC ≥ 95%
Description

This is a mutated b-Amyloid 1 to 28 amino acids sequence in which the KLVFF sequence (Ab16-20) is substituted with AAVFA. The KLVFF is the shortest peptide displaying consistent high binding capacity to full-length Ab. The first, second, and fifth residues (i.e. KLXXF) are critical for binding. The substitutions in this Ab (1-28) amino acids sequence in the 16 to 20 region profoundly impair the ability of the peptide to aggregate and form amyloid-like fibrils.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Tjernberg, L. et al. J. Biol. Chem. 271, 8545 (1996).
Molecular Weight 3087.2
Sequence
(One-Letter Code)
DAEFRHDSGYEVHHQAAVFAAEDVGSNK
Sequence
(Three-Letter Code)
H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Ala - Ala - Val - Phe - Ala - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - OH
     
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