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Peptides  >  Enzyme Substrates and Inhibitors  >>  Suc-LLVY-AMC, fluorogenic substrate

Product Name Suc - LLVY - AMC, fluorogenic substrate
Suc - LLVY - AMC
Size 5 mg
Catalog # 63892
US$ $83
Purity % Peak Area By HPLC ≥ 95%
Description

This 7-amino-4-methylcoumarin (AMC) labeled peptide is widely used as a fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorimetrically at Abs/Em=353/442 nm.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
Molecular Weight 763.9
Sequence
(One-Letter Code)
Suc-LLVY-AMC
Sequence
(Three-Letter Code)
Suc - Leu - Leu - Val - Tyr - AMC
Product Citations Dammer, E. et al. (2011). Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease. J Biol Chem doi: 10.1074/jbc.M110.149633.
Gallery, M. et al. (2007). The JAMM motif of human deubiquitinase Poh1 is essential for cell viability. Mol Cancer Ther 6, 262.
     
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