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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Me1)4]-Histone H3 (1-21), H3K4(Me1)

Product Name [Lys(Me1)4] - Histone H3 (1 - 21), H3K4(Me1)
ART - K(Me1) - QTARKSTGGKAPRKQLA
Size 1 mg
Catalog # AS-64459
US$ $297
Purity % Peak Area By HPLC ≥ 95%
Description

This is a monomethylated lysine at position 4 of the 1-21 amino acid histone H3 peptide. This form of histone methylation is characterized as being enriched around transcription start sites. Itís chromatin mark was also closely correlated to cell-type specific expression of putative gene targets of enhancers. It was also noted from a genome wide study that most potential regulatory elements were enriched only by the mono-methylated version of this histone 3.

Storage -20įC
References 1, Tian Y. et al. PLOS One. 6(11):e27770 (2011).
2, Ortega-Velazquez, R. et al. FASEB. 17, 1529 (2003).
Molecular Weight 2268.6
Sequence
(One-Letter Code)
ART-K(Me1)-QTARKSTGGKAPRKQLA
Sequence
(Three-Letter Code)
H - Ala - Arg - Thr - Lys(Me1) - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - OH
Product Citations Sakane, C. et al. (2015). Measurement of lysine-specific demethylase-1 activity in the nuclear extracts by flow-injection based time-of-flight mass spectrometry. J Clin Biochem Nutr562:123-131. doi: 10.3164/jcbn.14-99.
     
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