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Peptides  >  p53 Peptides  >>  [Lys(Ac)382]-p53 (374-389); p53 acetylated K382

Product Name [Lys(Ac)382] - p53 (374 - 389); p53 acetylated K382
Ac - GQSTSRHK - K(Ac) - LMFKTEG - NH2
Size 1 mg
Catalog # AS-64394
US$ $132
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a p53 tumor suppressor protein acetylated at lysine 382 upon Ras expression, an event that is essential for its biological function. Acetylation at lysine 382 specifically determines the PAb421 epitope. p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair.

Storage -20C
Molecular Weight 1918.2
Sequence
(One-Letter Code)
Ac-GQSTSRHK-K(Ac)-LMFKTEG-NH2
Sequence
(Three-Letter Code)
Ac - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys(Ac) - Leu - Met - Phe - Lys - Thr - Glu - Gly - NH2
     
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