IGRP Catalytic Subunit - related Protein (206 - 214)
% Peak Area By HPLC ≥ 95%
This peptide is the ?-cell peptide corresponding to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and islet-specific glucose-6-phosphatase catalytic subunit related protein (IGRP) induce diabetes in non-obese diabetic (NOD) mice.
Krishnamurthy, B. et al. J. Immunol. 180,4458 (2008); Han, B. et al. J. Clin. Invest.115, 1879 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Val - Tyr - Leu - Lys - Thr - Asn - Val - Phe - Leu - OH