EMP17 is an erythropoietin (EPO)-mimetic peptide. Erythropoietin (EPO) is the hormone involved in red blood cell production, which activates its receptor by binding to the receptor's extracellular domain and presumably dimerizing two receptor monomers to initiate signal transduction. EMP contains two potentially reactive amines, one at the amino terminus of the peptide and one in the side chain of the single lysine within the peptide sequence.
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Thr - Tyr - Ser - Cys - His - Phe - Gly - Pro - Leu - Thr - Trp - Val - Cys - Lys - Pro - Gln - Gly - Gly - OH