This is a synthetic retroviral envelope peptide corresponding to a region highly conserved in retroviral transmembrane proteins such as pl5E. The CKS-17 peptide has been previously shown to inhibit monocyte superoxide production, natural killer cell activity, polyclonal B-cell activation, and monocyte-mediated killing by inactivation of interleukin-1.
Nelson, M. et al. Cancer Immunol Immunother30, 113 (1989).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Leu - Gln - Asn - Arg - Arg - Gly - Leu - Asp - Leu - Leu - Phe - Leu - Lys - Glu - Gly - Gly - Leu - OH