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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Me1)36]-Histone H3 (26-46)-K(Biotin), H3K36(Me1), Schizosaccharomyces octosporus

Product Name [Lys(Me1)36] - Histone H3 (26 - 46) - K(Biotin), H3K36(Me1), Schizosaccharomyces octosporus
RKAAPATGGV - K(Me1) - KPHRYRPGTV - K(BIOTIN)
Size 0.25 mg
Catalog # AS-64602-025
US$ $115
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a synthetic peptide corresponding to amino acids 26 to 46 of Schizosaccharomyces octosporus histone H3. It is also monomethylated at lysine-36, followed by a biotinylated lysine. The methylation of histone H3 at lysine 36 (K36) has recently been shown to be associated with RNA polymerase II (Pol II) elongation in Saccharomyces cerevisiae. Histone methylation also plays a key role in the regulation of chromatin structure and function. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Baetz, K. et al. Mol Cell Biol 26, 7871 (2006).
Molecular Weight 2616.1
Sequence
(One-Letter Code)
RKAAPATGGV-K(Me1)-KPHRYRPGTV-K(BIOTIN)
Sequence
(Three-Letter Code)
H - Arg - Lys - Ala - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys(Me1) - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Thr - Val - Lys(BIOTIN) - OH
Product Citations Adhikary, S. et al. (2015). Selective recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of all-trans-retinoic acid (ATRA)-responsive genes by putative chromatin reader ZMYND8 J. Biol. Chem. 291 2664-2681 doi: 10.1074/jbc.M115.679985
     
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