This peptide is Histone H4 (1-23). It is monomethylated at lysine 20 with a C-terminal GG linker, followed by a biotinylated lysine. The monomethylation of histone H4 at lysine 20 is proposed to be a crucial mark for chromosomal memory. It is also very active throughout the cell cycle and is abundant during S phase. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Schotta, G., et al., Genes Dev22, 15 (2008).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys(Me1) - Val - Leu - Arg - Gly - Gly - Lys(Biotin) - NH2