This peptide is amino acids 686 to 700 fragment containing the second LXXLL motif, derived from NR box II of steroid receptor coactivator (SRC1). Coactivator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription.
Urizar, N. et al. Science296, 1703 (2002); Parks, D. et al. Science284, 1365 (1999).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Arg - His - Lys - Ile - Leu - His - Arg - Leu - Leu - Gln - Glu - Gly - Ser - Pro - Ser - OH