This peptide is Histone H3 amino acid residues 1-21 with a C-terminal GG linker followed by a biotinylated lysine. It is symmetrically dimethylated at arginine 2 with a methyl group added to each nitrogen of the guanidinium group. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Klose, R. et al. Nat Rev Mol Cell Biol8, 307 (2007).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg(Me2s) - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2