This peptide is Histone H2B amino acid residues 1-22. It is acetylated at lysine 12 with a C-terminal GG linker followed by a biotinylated lysine. The acetylated histone H2B at lysine 12 is a target for autoantibodies in systemic lupus erythematosus when it is apoptosis-induced. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Van Bavel, CC. et al. Mol Immunol47, 2 (2009).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Pro - Glu - Pro - Ala - Lys - Ser - Ala - Pro - Ala - Pro - Lys - Lys(Ac) - Gly - Ser - Lys - Lys - Ala - Val - Thr - Lys - Ala - Gln - Gly - Gly - Lys(Biotin) - NH2