This is a biotin-labeled Smac/Diablo Peptide (Abs/Em=492/518 nm), which serves as a Livin inhibitor. Livin prevents apoptosis and sensitizes Livin-expressing cells to chemotherapy. This peptide has the potential to be used as a therapeutic agent for cancer treatment.
Chang, H. et al. Mol Cancer Ther6, 24 (2007).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Val - Pro - Ile - Ala - Gln - Lys - Ser - Glu - Lys - Lys(Biotin) - NH2