This peptide is amino acids 420 to 429 fragment of Host Vascular Endothelial Growth Factor Receptor 2 (HER-2), derived from the EC2 region and also known as the neu oncogene H2-Dq-restricted epitope. HER-2 is a tumor-associated antigen expressed in breast cancer cells that may be used for the development of anti-angiogenesis tumor vaccines.
Paterson, Y. et al. Cancer Res66, 7748 (2006); Al-Rawi, N. et al. J Immunol182, 5537 (2009).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Pro - Asp - Ser - Leu - Arg - Asp - Leu - Ser - Val - Phe - OH