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Peptides  >  Enzyme Substrates and Inhibitors  >>  IRAK-1 (360-380); IRAK-4 Peptide Substrate

Product Name IRAK - 1 (360 - 380); IRAK - 4 Peptide Substrate
KKARFSRFAGSSPSQSSMVAR
Size 1 mg
Catalog # 64959
US$ $159
Purity % Peak Area By HPLC ≥ 95%
Description

This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4, derived from the IRAK-1 activation loop peptide amino acids 360 to 380. This peptide sequence contains Ser-376, one of the primary phospho-acceptor residues of IRAK-1. IRAK-4 phosphorylates IRAK-1 as a key step in regulation of inflammatory signaling pathways.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Hekmat-Nejad, M. et al. Biochem 49, 1495 (2010).
Molecular Weight 2285.6
Sequence
(One-Letter Code)
KKARFSRFAGSSPSQSSMVAR
Sequence
(Three-Letter Code)
H - Lys - Lys - Ala - Arg - Phe - Ser - Arg - Phe - Ala - Gly - Ser - Ser - Pro - Ser - Gln - Ser - Ser - Met - Val - Ala - Arg - OH
     
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