This is the GluR23A sequence, a control inactive peptide used as a mutant counterpart to glutamate receptor endocytosis inhibitor (GluR23Y), connected to an 11 amino acid cell permeable HIV Trans-Activator of Transcription (TAT) protein transduction domain (PTD). GluR23A is derived from GluR23Y amino acids 869 to 877, with Ala substituted for Tyr, and thus lacking essential phosphorylation sites.
Ahmadian, G. et al. EMBO J23, 1040 (2004); Wang, Y. et al. J Biol Chem279, 41267 (2004); Yu, S. et al. J Neurochem106, 889 (2008).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Ala - Lys - Glu - Gly - Ala - Asn - Val - Ala - Gly - OH