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Assay Kits  >  Cathepsin Assay Kits  >>  SensoLyte® Rh110 Cathepsin G Assay Kit *Fluorimetric*

Product Name SensoLyte® Rh110 Cathepsin G Assay Kit *Fluorimetric*
Size 1 kit
Catalog # 72186
US$ $435
Description

Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin G is the serine protease released by neutrophils upon their activation. Cathepsin G is currently being explored as a target for anti-inflammatory and anti-infective drugs. The SensoLyte® Rh110 Cathepsin G Assay Kit provides a convenient assay for high throughput screening of enzyme inhibitors or for continuous assay of enzyme activity utilizing a fluorogenic peptide. Upon enzyme cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=496/520 nm. The kit contains: • Rh110 based fluorogenic substrate (Ex/Em=490/520 nm upon cleavage) • Assay buffer • Human Cathepsin G • Inhibitor • Fluorescence reference standard for calibration • A detailed protocol Kit size: 100 assays (96-well plate)

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
     
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