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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Ac)36]-Histone H3 (21-44)-GK(Biotin), H3K36(Ac), biotin-labeled

Product Name [Lys(Ac)36] - Histone H3 (21 - 44) - GK(Biotin), H3K36(Ac), biotin - labeled
ATKAARKSAPATGGV - K(Ac) - KPHRYRPGG - K(Biotin)
Size 1 mg
Catalog # AS-64936-1
US$ $335
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is Histone H3 (21-44). It is acetylated at lysine 36 with a C-terminal G linker followed by a biotinylated lysine. The acetylation of histone H3 at lysine (K) 36 is highly conserved in mammals and is mainly localized to the promoters of RNA polymerase II-transcribed genes. The transition between the acetylation and methylation of K36 acts as an “acetyl/methyl switch”, controlling chromatin function along transcription units. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20°C
References Morris, S. et al. J Biol Chem 282, 7632.
Molecular Weight 2959.5
Sequence
(One-Letter Code)
ATKAARKSAPATGGV-K(Ac)-KPHRYRPGG-K(Biotin)
Sequence
(Three-Letter Code)
H - Ala - Thr - Lys - Ala - Ala - Arg - Lys - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys(Ac) - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Gly - Lys(Biotin) - OH
     
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